N-METHYL-1-[3-(1H-PYRAZOL-1-YL)PHENYL]METHANAMINE DIHYDROCHLORIDE
N-Methyl-1-[3-(1H-pyrazol-1-yl)phenyl]methanaminedihydrochloride
CAS: 1185294-98-7
Molecular Formula: C11H15Cl2N3
N-METHYL-1-[3-(1H-PYRAZOL-1-YL)PHENYL]METHANAMINE DIHYDROCHLORIDE - Names and Identifiers
N-METHYL-1-[3-(1H-PYRAZOL-1-YL)PHENYL]METHANAMINE DIHYDROCHLORIDE - Physico-chemical Properties
| Molecular Formula | C11H15Cl2N3 |
| Molar Mass | 260.16 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD06801104 |
N-METHYL-1-[3-(1H-PYRAZOL-1-YL)PHENYL]METHANAMINE DIHYDROCHLORIDE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
N-METHYL-1-[3-(1H-PYRAZOL-1-YL)PHENYL]METHANAMINE DIHYDROCHLORIDE - Introduction
N-Methyl-1-[3-(1H-pyrazol-1-yl)phenyl]methanamine dihydrochloride (N-Methyl-1-[3-(1H-pyrazol-1-yl)phenyl]methanaminedihydrochloride) is a compound with the following properties and uses:
Nature:
-Appearance: White crystalline solid
-Formula: C13H14N4 • 2HCl
-Molecular weight: 313.2g/mol
-Melting point: 170-174°C
-Solubility: Soluble in water and organic solvents
Use:
N-Methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine dihydrochloride has some important applications in the field of medicine, including:
-as a synthetic intermediate for non-steroidal anti-inflammatory drugs
-For the synthesis of biologically active compounds and drug candidate compounds
Preparation Method:
N-Methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine dihydrochloride can be synthesized by the following steps:
1. In an appropriate solvent, benzamide and p-bromobenzaldehyde are reacted to generate N-methyl -1-[3-(bromobenzyl) phenyl] methylamine.
2. The reaction product of the first step is reacted with pyrrole aldehyde to generate the target product N-methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine.
3. Finally, the target product is treated with hydrochloric acid to generate N-methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine dihydrochloride.
Safety Information:
Specific safety information on this compound may require reference to the relevant Safety Data Sheet (SDS). In general, when handling chemicals, the following safety practices need to be observed:
-Wear appropriate personal protective equipment, such as lab gloves and safety glasses.
-Avoid contact with skin, eyes and inhalation of dust or gas.
-Operate in a well-ventilated area.
-Store in a dry, cool place, away from combustibles.
Please note that specific safety procedures and risk assessments should be conducted by experienced chemical professionals to ensure safe handling and proper use of the compound.
Nature:
-Appearance: White crystalline solid
-Formula: C13H14N4 • 2HCl
-Molecular weight: 313.2g/mol
-Melting point: 170-174°C
-Solubility: Soluble in water and organic solvents
Use:
N-Methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine dihydrochloride has some important applications in the field of medicine, including:
-as a synthetic intermediate for non-steroidal anti-inflammatory drugs
-For the synthesis of biologically active compounds and drug candidate compounds
Preparation Method:
N-Methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine dihydrochloride can be synthesized by the following steps:
1. In an appropriate solvent, benzamide and p-bromobenzaldehyde are reacted to generate N-methyl -1-[3-(bromobenzyl) phenyl] methylamine.
2. The reaction product of the first step is reacted with pyrrole aldehyde to generate the target product N-methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine.
3. Finally, the target product is treated with hydrochloric acid to generate N-methyl -1-[3-(1H-pyrazol-1-yl) phenyl] methylamine dihydrochloride.
Safety Information:
Specific safety information on this compound may require reference to the relevant Safety Data Sheet (SDS). In general, when handling chemicals, the following safety practices need to be observed:
-Wear appropriate personal protective equipment, such as lab gloves and safety glasses.
-Avoid contact with skin, eyes and inhalation of dust or gas.
-Operate in a well-ventilated area.
-Store in a dry, cool place, away from combustibles.
Please note that specific safety procedures and risk assessments should be conducted by experienced chemical professionals to ensure safe handling and proper use of the compound.
Last Update：2024-04-09 21:00:56
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N-METHYL-1-[3-(1H-PYRAZOL-1-YL)PHENYL]METHANAMINE DIHYDROCHLORIDE
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